Simarubàcia, Simarubàcies o Simaroubaceae és una família de plantes amb flors. Sobre la seva classificació taxonòmica hi ha hagut un important debat. Họ (familia), Simaroubaceae . “The Ecological Impact of Allelopathy in Ailanthus altissima (Simaroubaceae)”. American “Simaroubàceae—Ailanthus family”. Euleria (Anacardiaceae) is Pier asma (Simaroubaceae): The genus genera of Simaroubaceae and species of Picrasma. .. Palinología de la familia.

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Chemical constituents of plants from the genus Simaba Simaroubaceae. Quassinoids exhibit greater selectivity against Plasmodium falciparum than aginst Entamoeba histolytica, Giardia intestinalis or Toxoplasma gondii in vitro. Picrasin k, a new quassinoid from Quassia amara L.

An updated phylogenetic classification of the flowering plants. Los granos de polen de simaroubaceae. Quassiol A, a novel simzroubaceae triterpene from Quassia multifrora.

Simaroubaceae family: botany, chemical composition and biological activities

Discussion and Conclusion This paper is a review of the botanical, chemical and pharmacological characteristics of the major genera and species of Simaroubaceae family. The Simarubaceae family is botanically related to the Rutaceae, Meliaceae and Burseraceae families, though, in this group, it is more related to the first one in terms of chemical composition, wood anatomy, lack of resin ducts in the bark and in the free stamens. Y Castela coccinea Griseb.

Polyandrol, a C19 quassinoid from Castela polyandra. Cytotoxic against lymphocytic leukaemia, human nasopharynx carcinoma and human mammary adenocarcinoma.

Chaparrolide and castela nolide, new bitter smiaroubaceae from Castela nicholsoni. New antiulcer quassinoids from Eurycroma longifolia.


In vitro studies of the anthelmintic activity of Picrolemma sprucei Hook. Years later, Engler recognized three tribes: Quassinoid constituents from the twigs and thorns of Castela polyandra.

Many genera of this family are employed in the treatment of malaria, cancer, worms, viruses, gastritis, ulcer, inflammation, diarrhea and diabetes, in addition to their insecticide, healing and tonic activities. The last classification of Englerthe most used, was based on the number and nature of the carpels and styles, number and position of ovules, ramilia or absence of scales at the filaments’ base and composition of the leaf.

Simalikalactone D is responsible for the antimalarial properties of an amazonian traditional sumaroubaceae made with Quassia amara L. Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma spruce hook. Antidiabetic activity of standardized extraxt of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats.

Plos One 4, e Non-quassinoid constituents from the twigs and thorns of Castela polyandra. New toxic quassinoid glucosides from Simarouba glauca. Quassimarin, isolated from Quassia amara, showed activity against lymphocytic leukemia in rats, and carcinoma nasopharynx cells in human Kupchan and Streelman, Simaroubeae, Harrisonieae, Ailantheae and Spathelieae. Furthermore, Jiang and Zhou demonstrated the activity of four alkaloids, also derived from canthinone, isolated from Picrasma quassioides, against nasopharynx carcinoma cells.

A new neoquassin derivative from Quassia amara. How to cite this article. Triterpenos e alcaloide tipo cantinona dos galhos de Simaba polyphylla Cavalcante W. Indole alkaloids and quassin from Quassia africana.

Simarubàcies – Viquipèdia, l’enciclopèdia lliure

Anti-hiv activity of quassinoids. Standardized quassinoidrich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic-pituitarygonadal axis. Nevertheless, many of its species have not been studied or remain unexplored. Quassiols B-D, new squalene triterpenes from Quassia multiflora. Indole alkaloids from Quassia amara.


Antifertility activity of Quassia amara in male rats: Triterpenes Twenty triterpenes have been reported in six different species of the genus Simaba Barbosa et al. Among the alkaloids isolated from the different genera of the Simaroubaceae family Chart 1the canthines deserve special attention. This chemical diversity and the pharmacological activities of the isolated compounds; such as cytotoxicity, antimalarial, insecticidal, antitumor, hypoglycemic, antiulcer activities, among others, characterize the species of this particular family.

This family is characterized by the presence of quassinoids, secondary metabolites responsible of a wide spectrum of biological activities such as antitumor, antimalarial, antiviral, insecticide, feeding deterrent, amebicide, antiparasitic and herbicidal.

The main distribution hot spots are located at tropical areas of America, extending to Africa, Madagascar and regions of Australia bathed by the Pacific.


Brucea ntin is the main compound studied due to its noted antileukemic activity, which has enabled its use in clinical tests at the United States National Cancer Institute Polonsky et al. The chemical compounds of this nature were, initially, known as “quassin”, after a physician named Quassi used the bark of Simaroubaceae plants to treat fever.

Once the references were obtained, those considered relevant were selected.